Yes, quite possible.
As something to look at that is.
Passing at an estimated 167LDs from us, it won't be and isn't anything to worry about.

NASA'S info on it

http://www.space.com/19973-comet-ison.html

"During the period when Comet ISON is closest to the sun, it will actually pass in front of the sun as seen from behind [one of the satellites]," the agency added. "This opens up the exciting possibility that we might see extreme-ultraviolet emission from the comet, as was seen recently with the bright sungrazing Comet Lovejoy."

"What's known for sure, however, is ISON poses no threat to Earth. At its closest approach it will still be 40 million miles (64 million km) from Earth, just under half the distance between the planet and the sun. "